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The origins of these cards can be traced back to 1880s America, when blank cards known as stiffeners were put into paper packets in order to stiffen the packaging and protect the cigarettes from being crushed and bent

As Sid Lowe reports in Fear and Loathing in La Liga - if you haven't done so already, get on it in time for Christmas - Zamora was "a friend of the tango singer Carlos Gardel, consumer of three packets of cigarettes a day and countless cognacs" and "a famous night bird during the 1920s when Barcelona became the most fashionable city in Spain"

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Clinical trials supported by other organizations can be found on the ClinicalTrials.gov website