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This upregulates a wide array of protective genes, including enzymatic antioxidants (e.g., HO-1, NQO1) and components of GSH synthesis, significantly enhancing cellular capacity to neutralize oxidants

Before human translation, essential parameters to define: optimal dosing, infusion/administration route, frequency, biomarkers to monitor (senescent cell burden, inflammatory cytokines, organ function), long-term follow-up for adverse outcomes (especially tumour risk)

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