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Cameron JS, Trounce JR
They found DR progression in only the SUSTAIN 6 data, said Ashish Sharma, MD, at Lotus Eye Hospital and Institute in Coimbatore, India
According to Gupta et al., the most abundant expression of GLP-1Rs in humans is found in the frontal cortex, implying that in humans, GLP-1 signaling may engage higher-order cortical mechanisms to regulate eating behavior, extending beyond homeostatic hunger to include executive functions such as impulse control, decision-making, and reward evaluation
These modify pain signaling but leave the damaged nerves exactly as damaged as they were before
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